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Literature summary extracted from

  • Hong, W.; Chen, L.; Liu, Y.; Gao, W.
    ATP hydrolysis is essential for Bag-1M-mediated inhibition of the DNA binding by the glucocorticoid receptor (2009), Biochem. Biophys. Res. Commun., 390, 77-81.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
7.4.2.3 Chlorocebus aethiops
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African green monkey
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.4.2.3 COS-7 cell
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Chlorocebus aethiops
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.4.2.3 ATP + H2O ATP hydrolysis needed by Bcl-2 associated athanogene 1M (Bag-1M), which interacts with the ATPase domain of Hsp70 to modulate the release of the substrate from Hsp70. ATP hydrolysis enhances Bag-1M-mediated inhibition of the DNA binding by the glucocorticoid receptor GR Chlorocebus aethiops ADP + phosphate
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Synonyms

EC Number Synonyms Comment Organism
7.4.2.3 Hsp70
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Chlorocebus aethiops