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Literature summary extracted from

  • Tenberken, O.; Thiermann, H.; Worek, F.; Reiter, G.
    Chromatographic preparation and kinetic analysis of interactions between tabun enantiomers and acetylcholinesterase (2010), Toxicol. Lett., 195, 142-146.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 (+)-tabun
-
 Homo sapiens
3.1.1.7 (+)-tabun
-
 Sus scrofa
3.1.1.7 (-)-tabun
-
 Homo sapiens
3.1.1.7 (-)-tabun
-
 Sus scrofa
3.1.1.7 additional information semi-preparative isolation of the tabun enantiomers, and analysis of inhibitory potential and kinetics, overview. Reactivation kinetics of tabun-inhibited AChE with obidoxime, overview. Aging of tabun-inhibited human AChE, kinetics are similar for the tabun enantiomers, overview Homo sapiens
3.1.1.7 additional information semi-preparative isolation of the tabun enantiomers, and analysis of inhibitory potential and kinetics, overview. Reactivation kinetics of tabun-inhibited AChE with obidoxime, overview Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.7 acetylthiocholine + H2O Homo sapiens
-
 acetate + thiocholine
-
 ?
3.1.1.7 acetylthiocholine + H2O Sus scrofa
-
 acetate + thiocholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Homo sapiens
-
-
-
3.1.1.7 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 erythrocyte
-
 Homo sapiens
-
3.1.1.7 erythrocyte
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetylthiocholine + H2O
-
 Homo sapiens acetate + thiocholine
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Sus scrofa acetate + thiocholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.7 AChE
-
 Homo sapiens
3.1.1.7 AChE
-
 Sus scrofa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.7 37
-
 assay at Homo sapiens
3.1.1.7 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.7 7.4
-
 assay at Homo sapiens
3.1.1.7 7.4
-
 assay at Sus scrofa

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.7 additional information
-
 additional information inhibition kinetics Homo sapiens
3.1.1.7 additional information
-
 additional information inhibition kinetics Sus scrofa