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Literature summary extracted from

  • Thornalley, P.J.; Waris, S.; Fleming, T.; Santarius, T.; Larkin, S.J.; Winklhofer-Roob, B.M.; Stratton, M.R.; Rabbani, N.
    Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance (2010), Nucleic Acids Res., 38, 5432-5442.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.5 methylglyoxal + glutathione Homo sapiens
-
 (R)-S-lactoylglutathione
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.5 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.5 A-549 cell
-
 Homo sapiens
-
4.4.1.5 MG-63 cell
-
 Homo sapiens
-
4.4.1.5 NCI-H460 cell
-
 Homo sapiens
-
4.4.1.5 NCI-H522 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.5 methylglyoxal + glutathione
-
 Homo sapiens (R)-S-lactoylglutathione
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.5 Glo1
-
 Homo sapiens
4.4.1.5 glyoxalase-1
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.5 glutathione
-
 Homo sapiens