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Literature summary extracted from

  • Shaikh, S.; Samanta, K.; Kar, P.; Roy, S.; Chakraborti, T.; Chakraborti, S.
    m-Calpain-mediated cleavage of Na+/Ca2+ exchanger-1 in caveolae vesicles isolated from pulmonary artery smooth muscle (2010), Mol. Cell. Biochem., 341, 167-180.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.53 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl) ester
-
 Bos taurus
3.4.22.53 calpeptin
-
 Bos taurus
3.4.22.53 MDL28170
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.53 vesicle in caveolae vesicles isolated from bovine pulmonary artery smooth muscle plasma membrane Bos taurus 31982
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.22.53 Ca2+ dependent on Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.53 28000
-
 1 * 80000 + 1 * 28000, SDS-PAGE Bos taurus
3.4.22.53 80000
-
 1 * 80000 + 1 * 28000, SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.53 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.53 pulmonary artery smooth muscle cell
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.53 Na+/Ca2+ exchanger-1 + H2O calcium-dependent proteolytic cleavage of Na+/Ca2+ exchanger-1 occurs in the caveolae vesicles Bos taurus 82 kDa fragment + ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.22.53 heterodimer 1 * 80000 + 1 * 28000, SDS-PAGE Bos taurus

Synonyms

EC Number Synonyms Comment Organism
3.4.22.53 m-calpain
-
 Bos taurus