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Literature summary extracted from

  • Kwan, J.C.; Taori, K.; Paul, V.J.; Luesch, H.
    Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena (2009), Mar. Drugs, 7, 528-538.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.36 lyngbyastatin 10
-
 Sus scrofa
3.4.21.36 lyngbyastatin 7
-
 Sus scrofa
3.4.21.36 lyngbyastatin 8
-
 Sus scrofa
3.4.21.36 lyngbyastatin 9
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.36 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.36 pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.36 succinyl-L-Ala-L-Ala-L-Ala-4-nitroanilide + H2O
-
 Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.36 elastase
-
 Sus scrofa

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.4.21.36 0.0000473
-
 in Tris-HCl (pH 8.0) Sus scrofa lyngbyastatin 7
3.4.21.36 0.00012
-
 in Tris-HCl (pH 8.0) Sus scrofa lyngbyastatin 10
3.4.21.36 0.000123
-
 in Tris-HCl (pH 8.0) Sus scrofa lyngbyastatin 8
3.4.21.36 0.00021
-
 in Tris-HCl (pH 8.0) Sus scrofa lyngbyastatin 9