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Literature summary extracted from
- Inhibition of the cystathionine-gamma-lyase/hydrogen sulfide pathway in rat vascular smooth muscle cells by cobalt-60 gamma radiation (2009), Chin. Med. J., 122, 326-330.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.4.1.1 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.4.1.1 | vascular smooth muscle cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.1 | L-cysteine + H2O | - |
Rattus norvegicus | sulfide + NH3 + pyruvate | - |
? |  |
| 4.4.1.1 | L-homoserine + H2O | - |
Rattus norvegicus | 2-oxobutanoate + NH3 + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.4.1.1 | CSE | - |
Rattus norvegicus |
| 4.4.1.1 | cystathionine-gamma-lyase | - |
Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.1 | pyridoxal 5'-phosphate | dependent on | Rattus norvegicus | |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 4.4.1.1 | Rattus norvegicus | cobalt-60 gamma radiation at doses of 14 Gy and 25 Gy decrease the cystathionine-gamma-lyase activity by 15.1% and 20.5%, respectively, and cystathionine-gamma-lyase mRNA expression by 29.3% and 38.2%, respectively | down |
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Release 2023.1 (January 2023)
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