Literature summary extracted from

Stroup, G.B.; Kumar, S.; Jerome, C.P.
Treatment with a potent cathepsin K inhibitor preserves cortical and trabecular bone mass in ovariectomized monkeys (2009), Calcif. Tissue Int., 85, 344-355.

Application

EC Number	Application	Comment	Organism
3.4.22.38	medicine	treatment with the potent cathepsin K inhibitor relacatib preserves cortical and trabecular bone mass in ovariectomized monkeys	Macaca fascicularis

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.22.38	relacatib	SB-462795	Macaca fascicularis

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.38	Macaca fascicularis	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

General Information

EC Number	General Information	Comment	Organism
3.4.22.38	physiological function	cathepsin K is involved in osteoclast-mediated bone resorption	Macaca fascicularis

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Release 2023.1 (January 2023)