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Literature summary extracted from
- A rapid assay for angiotensin-converting enzyme activity using ultra-performance liquid chromatography-mass spectrometry (2010), Biomed. Chromatogr., 24, 312-317.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.15.1 | caffeic acid | - |
Oryctolagus cuniculus |  |
| 3.4.15.1 | caffeoyl acetate | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | captopril | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | chlorogenic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | ferulic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | additional information | inhibitor structure-activity relationship, overview | Oryctolagus cuniculus | |
| 3.4.15.1 | resveratrol | - |
Oryctolagus cuniculus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.15.1 | Zn2+ | - |
Oryctolagus cuniculus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | commercial preparation | - |
Oryctolagus cuniculus | - |
| 3.4.15.1 | lung | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.15.1 | hippuryl-His-Leu + H2O | - |
Oryctolagus cuniculus | hippuric acid + His-Leu | - |
? | |
| 3.4.15.1 | additional information | ACE structure-activity relationship, overview | Oryctolagus cuniculus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.15.1 | More | ACE structure-activity relationship, overview | Oryctolagus cuniculus |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.15.1 | ACE | - |
Oryctolagus cuniculus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.15.1 | 37 | - |
assay at | Oryctolagus cuniculus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.15.1 | 8.3 | - |
assay at | Oryctolagus cuniculus |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 3.4.15.1 | 2.527 | - |
pH 8.3, 37°C | Oryctolagus cuniculus | caffeic acid | |
| 3.4.15.1 | 3.129 | - |
pH 8.3, 37°C | Oryctolagus cuniculus | caffeoyl acetate | |
| 3.4.15.1 | 6.359 | - |
pH 8.3, 37°C | Oryctolagus cuniculus | resveratrol | |
| 3.4.15.1 | 10.9 | - |
pH 8.3, 37°C | Oryctolagus cuniculus | ferulic acid | |
| 3.4.15.1 | 15.08 | - |
pH 8.3, 37°C | Oryctolagus cuniculus | chlorogenic acid | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.15.1 | physiological function | ACE plays an important role in the renin-angiotensin system | Oryctolagus cuniculus |
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