Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Mancardi, D.; Penna, C.; Merlino, A.; Del Soldato, P.; Wink, D.A.; Pagliaro, P.
    Physiological and pharmacological features of the novel gasotransmitter: hydrogen sulfide (2009), Biochim. Biophys. Acta, 87, 864-872.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.1 DL-propargylglycine
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.4.1.1 cytosol
-
 Mus musculus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.1 aorta
-
 Mus musculus
-
4.4.1.1 artery tail Mus musculus
-
4.4.1.1 blood vessel with a decreasing activity in tail artery, aorta and mesenteric arteries Mus musculus
-
4.4.1.1 kidney
-
 Mus musculus
-
4.4.1.1 liver
-
 Mus musculus
-
4.4.1.1 mesenteric artery
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cystathionine + H2O
-
 Mus musculus L-cysteine + 2-oxobutanoate + NH3
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Mus musculus sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cystine + H2O
-
 Mus musculus L-thiocysteine + pyruvate + NH3
-
 ?
4.4.1.1 L-homoserine + H2O
-
 Mus musculus 2-oxobutanoate + NH3 + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.1 CSE
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.1 pyridoxal 5'-phosphate
-
 Mus musculus

Expression

EC Number Organism Comment Expression
4.4.1.1 Mus musculus higher rate of H2S production corresponds to an up-regulation of CSE expression in liver and kidney up