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Literature summary extracted from

  • Sahara, S.; Yamashima, T.
    Calpain-mediated Hsp70.1 cleavage in hippocampal CA1 neuronal death (2010), Biochem. Biophys. Res. Commun., 393, 806-811.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.52 lysosomal membrane
-
 Macaca fuscata 5765
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.22.52 Ca2+ activates at 1.0 mM Macaca fuscata

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.52 Macaca fuscata
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.52 cornu ammonis
-
 Macaca fuscata
-
3.4.22.52 cornu ammonis area 1 Macaca fuscata
-
3.4.22.52 neuron
-
 Macaca fuscata
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.52 Hsp70.1 + H2O Hsp70.1 in the CA-1 tissue is an in-vivo substrate of activated mu-calpain, carbonylated Hsp70.1 in the CA-1 tissue by artificial oxidative stressors such as hydroxynonenal or hydrogen peroxide is much more vulnerable to the calpain cleavage Macaca fuscata ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.22.52 mu-calpain
-
 Macaca fuscata