EC Number | Crystallization (Comment) | Organism |
---|---|---|
6.3.1.5 | to 1.9 A resolution | Francisella tularensis |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.1.5 | 0.2 | - |
deamido-NMN | - |
Francisella tularensis | |
6.3.1.5 | 5.82 | - |
deamido-NAD+ | - |
Francisella tularensis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.1.5 | Francisella tularensis | A0A0B3VMT3 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.1.5 | ATP + deamido-NAD+ + NH3 | - |
Francisella tularensis | AMP + diphosphate + NAD+ | - |
? | |
6.3.1.5 | ATP + deamido-NMN + NH3 | existence of an alternative route of NAD synthesis where the amidation of NaMN to nicotinamide mononucleotide occurs before the adenylylation reaction, which converts the intermediate to the NAD cofactor. The first step is catalyzed by Francisella tularensis NadE | Francisella tularensis | AMP + diphosphate + NMN | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.1.5 | 0.25 | - |
deamido-NAD+ | - |
Francisella tularensis | |
6.3.1.5 | 0.5 | - |
deamido-NMN | - |
Francisella tularensis |
EC Number | General Information | Comment | Organism |
---|---|---|---|
6.3.1.5 | physiological function | existence of an alternative route of NAD synthesis where the amidation of NaMN to nicotinamide mononucleotide occurs before the adenylylation reaction, which converts the intermediate to the NAD cofactor. The first step is catalyzed by Francisella tularensis NadE | Francisella tularensis |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.1.5 | 43 | - |
deamido-NAD+ | - |
Francisella tularensis | |
6.3.1.5 | 2500 | - |
deamido-NMN | - |
Francisella tularensis |