BRENDA - Enzyme Database show

Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia

Saleem, S.; Shah, Z.A.; Urade, Y.; Dore, S.; Neuroscience 160, 248-254 (2009)

Data extracted from this reference:

Application
EC Number
Application
Commentary
Organism
5.3.99.2
medicine
L-PGDS is beneficial for protecting the brain against transient and permanent cerebral ischemia, these results provide a better understanding of the role played by the enzymes that control eicosanoid synthesis and how they can be utilized as potential targets to prevent damage following either acute or potentially chronic neurological disorders
Mus musculus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Mus musculus
-
Prostaglandin D2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.2
Mus musculus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.2
brain
-
Mus musculus
-
5.3.99.2
central nervous system
-
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
705932
Mus musculus
Prostaglandin D2
-
-
-
?
Application (protein specific)
EC Number
Application
Commentary
Organism
5.3.99.2
medicine
L-PGDS is beneficial for protecting the brain against transient and permanent cerebral ischemia, these results provide a better understanding of the role played by the enzymes that control eicosanoid synthesis and how they can be utilized as potential targets to prevent damage following either acute or potentially chronic neurological disorders
Mus musculus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Mus musculus
-
Prostaglandin D2
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.2
brain
-
Mus musculus
-
5.3.99.2
central nervous system
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
705932
Mus musculus
Prostaglandin D2
-
-
-
?
Expression
EC Number
Organism
Commentary
Expression
5.3.99.2
Mus musculus
L-PGDS knockout mice are generated
down
Expression (protein specific)
EC Number
Organism
Commentary
Expression
5.3.99.2
Mus musculus
L-PGDS knockout mice are generated
down