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Literature summary extracted from

  • Miller, M.L.; Miller, D.L.
    Non-DNA-templated addition of nucleotides to the 3' end of RNAs by the mitochondrial RNA polymerase of Physarum polycephalum (2008), Mol. Cell. Biol., 28, 5795-5802.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.6 cloning of the cDNA for the mtRNAP of Physarum and expression in Escherichia coli Physarum polycephalum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.6 mitochondrion the enzyme in nucleus encoded and then transported to the mitochondrion Physarum polycephalum 5739
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.6 nucleoside triphosphate + RNAn Physarum polycephalum
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diphosphate + RNAn+1
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?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.6 Physarum polycephalum
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.6 additional information identification of an activity associated with the mtRNAP in which non-DNA-templated nucleotides are added to the 3' end of RNAs, any of the four rNTPs can act as precursors for this process, RNA editing mechanism, overview. Nucleotides that are not specified by the mitochondrial DNA templates are inserted into some RNAs, a process called RNA editing. This is an essential step in the expression of these RNAs, as the insertion of the nontemplated nucleotides creates open reading frames for the production of proteins from mRNAs or produces required secondary structure in rRNAs and tRNAs Physarum polycephalum ?
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?
2.7.7.6 nucleoside triphosphate + RNAn
-
Physarum polycephalum diphosphate + RNAn+1
-
?
2.7.7.6 nucleoside triphosphate + RNAn supercoiled, double-stranded DNA template is more efficient than that from nonsupercoiled DNA, in vitro transcription activity and mechanism, overview Physarum polycephalum diphosphate + RNAn+1
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?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.6 mitochondrial RNA polymerase
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Physarum polycephalum
2.7.7.6 mtRNAP
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Physarum polycephalum