Any feedback?
Literature summary extracted from
- Purification and biochemical characterization of four iron superoxide dismutases in Trypanosoma cruzi (2008), Mem. Inst. Oswaldo Cruz, 103, 271-276.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.15.1.1 | H2O2 | - |
Trypanosoma cruzi |  |
| 1.15.1.1 | additional information | no inhiibtion by CN- | Trypanosoma cruzi |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.15.1.1 | cytosol | all four isozymes mainly | Trypanosoma cruzi | 5829 | - |
| 1.15.1.1 | mitochondrion | isozyme SODIII | Trypanosoma cruzi | 5739 | - |
| 1.15.1.1 | additional information | SODI and SODII also occur in low mass organelles | Trypanosoma cruzi | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.15.1.1 | 20000 | - |
SODI, native PAGE | Trypanosoma cruzi |
| 1.15.1.1 | 25000 | - |
SODIV, native PAGE | Trypanosoma cruzi |
| 1.15.1.1 | 50000 | - |
SODIII, native PAGE | Trypanosoma cruzi |
| 1.15.1.1 | 60000 | - |
SODII, native PAGE | Trypanosoma cruzi |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.15.1.1 | 2 O2.- + 2 H+ | Trypanosoma cruzi | - |
O2 + H2O2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.15.1.1 | Trypanosoma cruzi | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.15.1.1 | four isozymes by ammonium sulfate fractionation, anion exchange chromatography, and gel filtration. SODI is purified 424fold, SODII 635fold, SODIII 336fold, and SODIV 489fold | Trypanosoma cruzi |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.15.1.1 | epimastigote | - |
Trypanosoma cruzi | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.15.1.1 | 7381 | - |
purified SODIII | Trypanosoma cruzi |
| 1.15.1.1 | 9446 | - |
purified SODI | Trypanosoma cruzi |
| 1.15.1.1 | 10750 | - |
purified SODIV | Trypanosoma cruzi |
| 1.15.1.1 | 13960 | - |
purified SODII | Trypanosoma cruzi |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.15.1.1 | 2 O2.- + 2 H+ | - |
Trypanosoma cruzi | O2 + H2O2 | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.15.1.1 | SOD I | - |
Trypanosoma cruzi |
| 1.15.1.1 | SODII | - |
Trypanosoma cruzi |
| 1.15.1.1 | SODIII | - |
Trypanosoma cruzi |
| 1.15.1.1 | SODIV | - |
Trypanosoma cruzi |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.15.1.1 | 7.8 | - |
assay at | Trypanosoma cruzi |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 1.15.1.1 | Trypanosoma cruzi | SODIV, isoelectric focussing | - |
3.8 |
| 1.15.1.1 | Trypanosoma cruzi | SODIII, isoelectric focussing | - |
5.2 |
| 1.15.1.1 | Trypanosoma cruzi | SODII, isoelectric focussing | - |
6.8 |
| 1.15.1.1 | Trypanosoma cruzi | SODI, isoelectric focussing | - |
6.9 |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
