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Literature summary extracted from

  • Sarkar, P.; Bharill, S.; Gryczynski, I.; Gryczynski, Z.; Nair, M.; Lacko, A.
    Binding of 8-anilino-1-naphthalenesulfonate to lecithin:cholesterol acyltransferase studied by fluorescence techniques (2008), J. Photochem. Photobiol. B Biol., 92, 19-23.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.43 phosphatidylcholine + cholesterol Homo sapiens
-
 cholesteryl ester + lysophosphatidylcholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.43 recombinant LCAT from the conditioned medium of engineered human lung cells Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 additional information study of enzyme interactions with macromolecules and conformational changes upon binding by labeling of tryptophan with 8-anilino-1-naphthalenesulfonate, ANS, steady-state and time-resolved fluorescence emission and anisotropies, Foerster resonance energy transfer, FRET, mechanism, method development and evaluation, overview Homo sapiens ?
-
 ?
2.3.1.43 phosphatidylcholine + cholesterol
-
 Homo sapiens cholesteryl ester + lysophosphatidylcholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.43 LCAT
-
 Homo sapiens
2.3.1.43 lecithin:cholesterol acyltransferase
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.43 7.4
-
 assay at Homo sapiens