Literature summary extracted from

Schauff, A.; Kim, E.; Leppert, J.; Nadrowitz, R.; Wuestenberg, R.; Brockmann, M.; Giese, A.
Inhibition of invasion-associated thromboxane synthase sensitizes experimental gliomas to gamma-radiation (2009), J. Neurooncol., 91, 241-249.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
5.3.99.5	furegrelate	specific inhibitor of thromboxane synthase, i.e. sodium 5-(3-pyridinylmethyl) benzofuran-2-carboxylate	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5.3.99.5	prostaglandin H2	Homo sapiens	-	thromboxane B2 + 12(S)-hydroxy-5,8,10-heptadecatrienoic acid	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.3.99.5	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
5.3.99.5	glioma cell	-	Homo sapiens	-
5.3.99.5	U-87MG cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.3.99.5	prostaglandin H2	-	Homo sapiens	thromboxane B2 + 12(S)-hydroxy-5,8,10-heptadecatrienoic acid	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
5.3.99.5	thromboxane synthase	-	Homo sapiens
5.3.99.5	TXSA	-	Homo sapiens

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Release 2023.1 (January 2023)