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Literature summary extracted from

  • Mansilla, F.; da Costa, K.A.; Wang, S.; Kruh?ffer, M.; Lewin, T.M.; Orntoft, T.F.; Coleman, R.A.; Birkenkamp-Demtroeder, K.
    Lysophosphatidylcholine acyltransferase 1 (LPCAT1) overexpression in human colorectal cancer (2009), J. Mol. Med., 87, 85-97.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.23 expressed in COS-7 cell and SW-480 cell Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.23 M427T naturally occuring mutation, does not significantly affect the activity or function Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Homo sapiens Q8NF37
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 colorectal adenocarcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 linoleoyl-CoA + 1-palmitoyl-2-lysophosphatidylcholine
-
 Homo sapiens CoA + 1-palmitoyl-2-linoleoylphosphatidylcholine
-
 ?
2.3.1.23 palmitoyl-CoA + 1-palmitoyl-2-lysophosphatidylcholine
-
 Homo sapiens CoA + 1,2-dipalmitoylphosphatidylcholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.23 LPCAT1
-
 Homo sapiens
2.3.1.23 lysophosphatidylcholine acyltransferase 1
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
2.3.1.23 Homo sapiens upregulated in colorectal adenocarcinomas (compared to normal mucosas) up