EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.1.64 | F61L | the mutant shows 1.02% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | F61W | the mutant shows 1.28% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | F61Y | the mutant shows 7.57% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | T147A | the mutant shows 12.63% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | T147C | the mutant shows 20.18% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | T147G | the mutant shows 30.02% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | T147S | the mutant shows 84% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | T147V | inactive | Homo sapiens |
3.1.1.64 | T147W | inactive | Homo sapiens |
3.1.1.64 | T147Y | inactive | Homo sapiens |
3.1.1.64 | W331F | the mutant shows 8.34% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | W331L | inactive | Homo sapiens |
3.1.1.64 | W331Q | inactive | Homo sapiens |
3.1.1.64 | W331Y | the mutant shows 26.72% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | Y239C | inactive | Homo sapiens |
3.1.1.64 | Y239D | inactive | Homo sapiens |
3.1.1.64 | Y239F | inactive | Homo sapiens |
3.1.1.64 | Y239L | inactive | Homo sapiens |
3.1.1.64 | Y239S | inactive | Homo sapiens |
3.1.1.64 | Y239T | inactive | Homo sapiens |
3.1.1.64 | Y239W | inactive | Homo sapiens |
3.1.1.64 | Y275F | the mutant shows 14.44% activity compared to the wild type enzyme | Homo sapiens |
3.1.1.64 | Y275I | inactive | Homo sapiens |
3.1.1.64 | Y275W | inactive | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.64 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.64 | all-trans-retinyl ester + H2O | - |
Homo sapiens | 11-cis-retinol + a fatty acid | - |
? | |
3.1.1.64 | additional information | RPE65 is not inherently 11-cis-specific and can produce both 11- and 13-cis isomers | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.64 | Rpe65 | - |
Homo sapiens |