EC Number | Cloned (Comment) | Organism |
---|---|---|
3.1.3.53 | various parts of myosin phosphatase targeting subunit GST-fusions expressed in Escherichia coli | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.3.53 | T696D | part of myosin phosphatase targeting subunit, inhibitory site | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.53 | fragment 654-880 of human myosin phosphatase targeting subunit GST-fusion | - |
Sus scrofa | |
3.1.3.53 | fragment 697-880 of human myosin phosphatase targeting subunit GST-fusion | - |
Sus scrofa | |
3.1.3.53 | additional information | phosphorylation of myosin phosphatase targeting subunit on Thr696 and Thr853 (inhibitory sites) results in inhibition | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.53 | Homo sapiens | - |
- |
- |
3.1.3.53 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.3.53 | GSH affinity chromatography | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.53 | aorta | - |
Sus scrofa | - |
3.1.3.53 | HeLa cell | - |
Homo sapiens | - |
3.1.3.53 | smooth muscle | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.53 | [myosin regulatory light chain] phosphate + H2O | from chicken gizzard | Sus scrofa | [myosin regulatory light chain] + phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.3.53 | myosin light chain phosphatase | - |
Homo sapiens |
3.1.3.53 | myosin light chain phosphatase | - |
Sus scrofa |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.1.3.53 | 0.0000011 | - |
- |
Sus scrofa | phosphorylated fragment 654-880 of human myosin phosphatase targeting subunit GST-fusion | |
3.1.3.53 | 0.00006 | - |
- |
Sus scrofa | phosphorylated fragment 697-880 of human myosin phosphatase targeting subunit GST-fusion | |
3.1.3.53 | 0.0014 | - |
- |
Sus scrofa | unphosphorylated fragment 654-880 of human myosin phosphatase targeting subunit GST-fusion | |
3.1.3.53 | 0.0061 | - |
- |
Sus scrofa | unphosphorylated fragment 697-880 of human myosin phosphatase targeting subunit GST-fusion |