BRENDA - Enzyme Database show

Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signaling in melanocytes

Takeda, K.; Takahashi, N.H.; Yoshizawa, M.; Shibahara, S.; J. Biochem. 148, 139-148 (2010)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
5.3.99.2
into the vectors pUB6/V5-His and pIRESneo, cDNA of positions 76-648 is cloned into the vector pGEM-T Easy
Homo sapiens
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.2
RNAi
-
Homo sapiens
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.2
extracellular
secreted in culture medium
Homo sapiens
-
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Homo sapiens
-
Prostaglandin D2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.2
Homo sapiens
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
5.3.99.2
collected from the media using a Ni-column
Homo sapiens
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.2
ARPE-19 cell
-
Homo sapiens
-
5.3.99.2
melanocyte
epidermal melanocyte
Homo sapiens
-
5.3.99.2
NHEM cell
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
704365
Homo sapiens
Prostaglandin D2
-
-
-
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
5.3.99.2
into the vectors pUB6/V5-His and pIRESneo, cDNA of positions 76-648 is cloned into the vector pGEM-T Easy
Homo sapiens
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.2
RNAi
-
Homo sapiens
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.2
extracellular
secreted in culture medium
Homo sapiens
-
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Homo sapiens
-
Prostaglandin D2
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
5.3.99.2
collected from the media using a Ni-column
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.2
ARPE-19 cell
-
Homo sapiens
-
5.3.99.2
melanocyte
epidermal melanocyte
Homo sapiens
-
5.3.99.2
NHEM cell
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
704365
Homo sapiens
Prostaglandin D2
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
5.3.99.2
physiological function
L-PGDS may fine-tune the all-trans retinoic acid signaling in melanocytes
Homo sapiens
General Information (protein specific)
EC Number
General Information
Commentary
Organism
5.3.99.2
physiological function
L-PGDS may fine-tune the all-trans retinoic acid signaling in melanocytes
Homo sapiens