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Literature summary extracted from

  • Takeda, K.; Takahashi, N.H.; Yoshizawa, M.; Shibahara, S.
    Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signaling in melanocytes (2010), J. Biochem., 148, 139-148.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.99.2 into the vectors pUB6/V5-His and pIRESneo, cDNA of positions 76-648 is cloned into the vector pGEM-T Easy Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.99.2 RNAi
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.99.2 extracellular secreted in culture medium Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.99.2 Prostaglandin H2 Homo sapiens
-
 Prostaglandin D2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.2 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.3.99.2 collected from the media using a Ni-column Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.99.2 ARPE-19 cell
-
 Homo sapiens
-
5.3.99.2 melanocyte epidermal melanocyte Homo sapiens
-
5.3.99.2 NHEM cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.2 Prostaglandin H2
-
 Homo sapiens Prostaglandin D2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.3.99.2 L-PGDS
-
 Homo sapiens
5.3.99.2 lipocalin-type prostaglandin d synthase
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
5.3.99.2 physiological function L-PGDS may fine-tune the all-trans retinoic acid signaling in melanocytes Homo sapiens