BRENDA - Enzyme Database show

The impact of microsomal prostaglandin E synthase 1 on blood pressure is determined by genetic background

Facemire, C.S.; Griffiths, R.; Audoly, L.P.; Koller, B.H.; Coffman, T.M.; Hypertension 55, 531-538 (2010)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.3
microsome
-
Mus musculus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.3
Mus musculus
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.3
Prostaglandin H2
-
703978
Mus musculus
Prostaglandin E2
-
-
-
?
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.3
microsome
-
Mus musculus
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.3
Prostaglandin H2
-
703978
Mus musculus
Prostaglandin E2
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
5.3.99.3
malfunction
baseline blood pressures are significantly higher in mPGES1-deficientanimals than wild type controls
Mus musculus
General Information (protein specific)
EC Number
General Information
Commentary
Organism
5.3.99.3
malfunction
baseline blood pressures are significantly higher in mPGES1-deficientanimals than wild type controls
Mus musculus