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Literature summary extracted from

  • Niimura, Y.; Moue, T.; Takahashi, N.; Nagai, K.I.
    Modification of sphingoglycolipids and sulfolipids in kidney cell lines under heat stress: Activation of monohexosylceramide synthesis as a ceramide scavenger (2010), Glycobiology, 20, 710-717.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.80 HSP70 dog heat shock protein 70 increases production of glucosylceramide to 149% Chlorocebus sabaeus
2.4.1.80 HSP70 dog heat shock protein 70 increases production of glucosylceramide to 207% Canis lupus familiaris

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.62 Canis lupus familiaris
-
-
-
2.4.1.62 Chlorocebus aethiops
-
-
-
2.4.1.80 Canis lupus familiaris
-
-
-
2.4.1.80 Canis lupus familiaris
-
 MDCK cells
-
2.4.1.80 Chlorocebus aethiops
-
-
-
2.4.1.80 Chlorocebus sabaeus
-
 COS7 cells
-
2.8.2.11 Canis lupus familiaris
-
-
-
2.8.2.11 Chlorocebus aethiops
-
-
-
2.8.2.11 Chlorocebus sabaeus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.62 COS-7 cell
-
 Chlorocebus aethiops
-
2.4.1.62 kidney cell line
-
 Canis lupus familiaris
-
2.4.1.62 MDCK cell
-
 Canis lupus familiaris
-
2.4.1.80 COS-7 cell
-
 Chlorocebus aethiops
-
2.4.1.80 kidney
-
 Canis lupus familiaris
-
2.4.1.80 kidney
-
 Chlorocebus sabaeus
-
2.4.1.80 kidney cell line
-
 Canis lupus familiaris
-
2.4.1.80 MDCK cell
-
 Canis lupus familiaris
-
2.8.2.11 COS-7 cell
-
 Chlorocebus aethiops
-
2.8.2.11 COS-7 cell
-
 Chlorocebus sabaeus
-
2.8.2.11 kidney
-
 Canis lupus familiaris
-
2.8.2.11 kidney
-
 Chlorocebus sabaeus
-
2.8.2.11 kidney cell line
-
 Canis lupus familiaris
-
2.8.2.11 MDCK cell
-
 Canis lupus familiaris
-

Synonyms

EC Number Synonyms Comment Organism
2.4.1.62 ceramide galactosyltransferase
-
 Canis lupus familiaris
2.4.1.62 ceramide galactosyltransferase
-
 Chlorocebus aethiops
2.4.1.62 GALT
-
 Canis lupus familiaris
2.4.1.62 GALT
-
 Chlorocebus aethiops
2.4.1.80 ceramide glucosyltransferase
-
 Canis lupus familiaris
2.4.1.80 ceramide glucosyltransferase
-
 Chlorocebus aethiops
2.4.1.80 ceramide glycosyltransferase
-
 Canis lupus familiaris
2.4.1.80 ceramide glycosyltransferase
-
 Chlorocebus sabaeus
2.4.1.80 GluT
-
 Canis lupus familiaris
2.4.1.80 GluT
-
 Chlorocebus aethiops
2.4.1.80 GluT
-
 Chlorocebus sabaeus
2.8.2.11 cerebroside sulfotransferase
-
 Canis lupus familiaris
2.8.2.11 cerebroside sulfotransferase
-
 Chlorocebus sabaeus
2.8.2.11 galactosylceramide sulfotransferase
-
 Canis lupus familiaris
2.8.2.11 galactosylceramide sulfotransferase
-
 Chlorocebus aethiops
2.8.2.11 GalCer sulfotransferase
-
 Canis lupus familiaris
2.8.2.11 GalCer sulfotransferase
-
 Chlorocebus aethiops
2.8.2.11 GalCer sulfotransferase
-
 Chlorocebus sabaeus
2.8.2.11 GST
-
 Canis lupus familiaris
2.8.2.11 GST
-
 Chlorocebus aethiops
2.8.2.11 GST
-
 Chlorocebus sabaeus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.2.11 37
-
 sulfoglycolipid synthesis is optimal at 37°C Canis lupus familiaris

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.8.2.11 37
-
 sulfoglycolipid synthesis is low at 40°C, and decreases to 4% at 42°C Canis lupus familiaris

Expression

EC Number Organism Comment Expression
2.4.1.62 Chlorocebus aethiops cell culture under 42°C heat stress for 17 h, increase of gene expression to 133% up
2.4.1.62 Canis lupus familiaris cell culture under 42°C heat stress for 24 h, increase of gene expression to 221% up
2.4.1.80 Canis lupus familiaris HSP70 influence on gene expression additional information
2.4.1.80 Chlorocebus aethiops HSP70 influence on gene expression additional information
2.4.1.80 Chlorocebus sabaeus after 17 h under a 42°C heat stress, GluT mRNA increased to 142% up
2.4.1.80 Canis lupus familiaris after 24 h under a 42°C heat stress, GluT mRNA significantly increased to 714% up
2.4.1.80 Chlorocebus aethiops cell culture under 42°C heat stress for 17 h, increase of gene expression to 142% up
2.4.1.80 Canis lupus familiaris cell culture under 42°C heat stress for 24 h, increase of gene expression to 714% up
2.8.2.11 Chlorocebus sabaeus after 17 h under a 42°C heat stress, GST mRNA increased to 148% up
2.8.2.11 Canis lupus familiaris after 24 h under a 42°C heat stress, GST mRNA increased to 174% up
2.8.2.11 Chlorocebus aethiops cell culture under 42°C heat stress for 17 h, increase of gene expression to 148% up
2.8.2.11 Canis lupus familiaris cell culture under 42°C heat stress for 24 h, increase of gene expression to 174% up