BRENDA - Enzyme Database show

Inhibition of thromboxane synthase induces lung cancer cell death via increasing the nuclear p27

Leung, K.C.; Hsin, M.K.; Chan, J.S.; Yip, J.H.; Li, M.; Leung, B.C.; Mok, T.S.; Warner, T.D.; Underwood, M.J.; Chen, G.G.; Exp. Cell Res. 315, 2974-2981 (2009)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.5
1-Benzylimidazole
special inhibitor of TXS
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.5
Homo sapiens
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.5
DMS-114 cell
-
Homo sapiens
-
5.3.99.5
lung cancer cell
-
Homo sapiens
-
5.3.99.5
NCI-H23 cell
-
Homo sapiens
-
5.3.99.5
non-small cell lung cancer cell
-
Homo sapiens
-
5.3.99.5
small cell lung carcinoma cell
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
prostaglandin H2
-
703584
Homo sapiens
thromboxane B2 + 12(S)-hydroxy-5,8,10-heptadecatrienoic acid
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.5
1-Benzylimidazole
special inhibitor of TXS
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.5
DMS-114 cell
-
Homo sapiens
-
5.3.99.5
lung cancer cell
-
Homo sapiens
-
5.3.99.5
NCI-H23 cell
-
Homo sapiens
-
5.3.99.5
non-small cell lung cancer cell
-
Homo sapiens
-
5.3.99.5
small cell lung carcinoma cell
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
prostaglandin H2
-
703584
Homo sapiens
thromboxane B2 + 12(S)-hydroxy-5,8,10-heptadecatrienoic acid
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
5.3.99.5
malfunction
inhibition of thromboxane synthase induces lung cancer cell death via increasing the nuclear p27
Homo sapiens
General Information (protein specific)
EC Number
General Information
Commentary
Organism
5.3.99.5
malfunction
inhibition of thromboxane synthase induces lung cancer cell death via increasing the nuclear p27
Homo sapiens