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Literature summary extracted from

  • Leung, K.C.; Hsin, M.K.; Chan, J.S.; Yip, J.H.; Li, M.; Leung, B.C.; Mok, T.S.; Warner, T.D.; Underwood, M.J.; Chen, G.G.
    Inhibition of thromboxane synthase induces lung cancer cell death via increasing the nuclear p27 (2009), Exp. Cell Res., 315, 2974-2981.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.99.5 1-Benzylimidazole special inhibitor of TXS Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.5 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.99.5 DMS-114 cell
-
 Homo sapiens
-
5.3.99.5 lung cancer cell
-
 Homo sapiens
-
5.3.99.5 NCI-H23 cell
-
 Homo sapiens
-
5.3.99.5 non-small cell lung cancer cell
-
 Homo sapiens
-
5.3.99.5 small cell lung carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.5 prostaglandin H2
-
 Homo sapiens thromboxane B2 + 12(S)-hydroxy-5,8,10-heptadecatrienoic acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.3.99.5 thromboxane synthase
-
 Homo sapiens
5.3.99.5 TXS
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
5.3.99.5 malfunction inhibition of thromboxane synthase induces lung cancer cell death via increasing the nuclear p27 Homo sapiens