EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.6 | TFB2 | the essential initiation factor forms a network of interactions with DNA near the transcription start site and facilitates promoter melting but may not be essential for promoter recognition, TFB2 bridges upstream and downstream promoter contacts of the initiation complex, mapping of TFB2-DNA interactions at the transcription start site, overview | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.7.6 | expression of the N-terminally His6-tagged intein fusion mitoRNAP protein | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.7.6 | G711K/N926S/N1103S/N1117S | site-directed mutagenesis, the mutant mitoRNAP that lacks four natural hydroxylamine cleavage sites | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.7.6 | mitochondrion | - |
Homo sapiens | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.6 | additional information | Homo sapiens | molecular mechanisms of transcription regulation in mitochondria, molecular organization of the human mitochondrial transcription initiation complex, overview | ? | - |
? | |
2.7.7.6 | nucleoside triphosphate + RNAn | Homo sapiens | - |
diphosphate + RNAn+1 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.6 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.6 | additional information | molecular mechanisms of transcription regulation in mitochondria, molecular organization of the human mitochondrial transcription initiation complex, overview | Homo sapiens | ? | - |
? | |
2.7.7.6 | nucleoside triphosphate + RNAn | - |
Homo sapiens | diphosphate + RNAn+1 | - |
? | |
2.7.7.6 | nucleoside triphosphate + RNAn | template is DNA | Homo sapiens | diphosphate + RNAn+1 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.7.6 | monomer | - |
Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.6 | mitoRNAP | - |
Homo sapiens |
2.7.7.6 | More | the enzyme belongs to the single-subunit, T7-like mitochondrial RNAP family | Homo sapiens |
2.7.7.6 | RNA polymerase | - |
Homo sapiens |
2.7.7.6 | RNAP | - |
Homo sapiens |
2.7.7.6 | T7 RNAP | - |
Homo sapiens |
2.7.7.6 | T7-like RNA polymerase | - |
Homo sapiens |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.7.6 | 35 | - |
assay at | Homo sapiens |