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Literature summary extracted from

  • Blechingberg, J.; Holm, I.E.; Johansen, M.G.; B?rglum, A.D.; Nielsen, A.L.
    Aromatic L-amino acid decarboxylase expression profiling and isoform detection in the developing porcine brain (2010), Brain Res., 1308, 1-13.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.28 54000
-
 deduced from amino acid sequence Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.28 L-Dopa Sus scrofa
-
 dopamine + CO2
-
 ?
4.1.1.28 L-Trp Sus scrofa
-
 Tryptamine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.28 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.28 basal ganglion both the neuronal and the extraneuronal AADC mRNA isoforms are present at early brain developmental stages in the basal ganglia Sus scrofa
-
4.1.1.28 brain AADC expression in the developing pig brain is highly expressed in the basal ganglia and the brain stem regions, and also significantly expressed in the cortex, the hippocampus and the cerebellum Sus scrofa
-
4.1.1.28 brain cortex
-
 Sus scrofa
-
4.1.1.28 brain stem both the neuronal and the extraneuronal AADC mRNA isoforms are present at early brain developmental stages in the brain stem Sus scrofa
-
4.1.1.28 cerebellum
-
 Sus scrofa
-
4.1.1.28 hippocampus
-
 Sus scrofa
-
4.1.1.28 liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.28 L-Dopa
-
 Sus scrofa dopamine + CO2
-
 ?
4.1.1.28 L-Trp
-
 Sus scrofa Tryptamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.28 AADC
-
 Sus scrofa
4.1.1.28 AADC393 isoform Sus scrofa
4.1.1.28 AADC438 isoform Sus scrofa
4.1.1.28 AADC486 isoform Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.28 pyridoxal 5'-phosphate
-
 Sus scrofa