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Literature summary extracted from

  • Miyake, Y.; Sakurai, M.; Tanaka, S.; Tunjung, W.A.; Yokoo, M.; Matsumoto, H.; Aso, H.; Yamaguchi, T.; Sato, E.
    Expression of hyaluronan synthase 1 and distribution of hyaluronan during follicular atresia in pig ovaries (2009), Biol. Reprod., 80, 249-257.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.212 Sus scrofa
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.212 macrophage HAS1 expression is shown in 55.7% of SIRPA-positive macrophages in stage III follicles Sus scrofa
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2.4.1.212 ovarian follicle expression of isoform HAS1 in theca cells of healthy and early atretic follicles of stage I and stage II and in progressing atretic stage III follicles Sus scrofa
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2.4.1.212 ovary
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 Sus scrofa
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2.4.1.212 theca cell expression of isoform HAS1 in theca cells of healthy and early atretic follicles of stage I and stage II and in progressing atretic stage III follicles Sus scrofa
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Expression

EC Number Organism Comment Expression
2.4.1.212 Sus scrofa during atresia, HAS1 mRNA and protein expression is markedly up-regulated inovary. HAS2 and HAS3 mRNA expression levels are low and very low to undetectable, respectively up

General Information

EC Number General Information Comment Organism
2.4.1.212 physiological function hyaluronan concentration in follicular fluids increases during atresia. Isoform HAS1 may be the dominant HAS protein in theca cells to produce hyaluronan in pig ovaries Sus scrofa