Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Cai, J.; Abramovici, H.; Gee, S.H.; Topham, M.K.
    Diacylglycerol kinases as sources of phosphatidic acid (2009), Biochim. Biophys. Acta, 1791, 942-948.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.107 cytosol
-
 Drosophila melanogaster 5829
-
2.7.1.107 cytosol
-
 Sus scrofa 5829
-
2.7.1.107 cytosol
-
 Arabidopsis thaliana 5829
-
2.7.1.107 cytosol
-
 Caenorhabditis elegans 5829
-
2.7.1.107 cytosol
-
 Mus musculus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.107 80000
-
 SDS-PAGE Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.107 Arabidopsis thaliana
-
-
-
2.7.1.107 Caenorhabditis elegans
-
-
-
2.7.1.107 Drosophila melanogaster
-
-
-
2.7.1.107 Mus musculus Q80UP3
-
-
2.7.1.107 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.107 brain
-
 Sus scrofa
-
2.7.1.107 myocardium
-
 Mus musculus
-
2.7.1.107 retina
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.107 ATP + 1,2-diacylglycerol
-
 Drosophila melanogaster ADP + 1,2-diacyl-sn-glycerol 3-phosphate 1,2-diacyl-sn-glycerol 3-phosphate is phosphatidic acid ir
2.7.1.107 ATP + 1,2-diacylglycerol
-
 Sus scrofa ADP + 1,2-diacyl-sn-glycerol 3-phosphate 1,2-diacyl-sn-glycerol 3-phosphate is phosphatidic acid ir
2.7.1.107 ATP + 1,2-diacylglycerol
-
 Arabidopsis thaliana ADP + 1,2-diacyl-sn-glycerol 3-phosphate 1,2-diacyl-sn-glycerol 3-phosphate is phosphatidic acid ir
2.7.1.107 ATP + 1,2-diacylglycerol
-
 Caenorhabditis elegans ADP + 1,2-diacyl-sn-glycerol 3-phosphate 1,2-diacyl-sn-glycerol 3-phosphate is phosphatidic acid ir
2.7.1.107 ATP + 1,2-diacylglycerol
-
 Mus musculus ADP + 1,2-diacyl-sn-glycerol 3-phosphate 1,2-diacyl-sn-glycerol 3-phosphate is phosphatidic acid ir

Synonyms

EC Number Synonyms Comment Organism
2.7.1.107 DGK
-
 Drosophila melanogaster
2.7.1.107 DGK
-
 Sus scrofa
2.7.1.107 DGK
-
 Arabidopsis thaliana
2.7.1.107 DGK
-
 Caenorhabditis elegans
2.7.1.107 DGKzeta isoform Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.107 ATP
-
 Drosophila melanogaster
2.7.1.107 ATP
-
 Sus scrofa
2.7.1.107 ATP
-
 Arabidopsis thaliana
2.7.1.107 ATP
-
 Caenorhabditis elegans
2.7.1.107 ATP
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.7.1.107 physiological function DGKs broadly regulate signaling events by virtue of their ability to provide 1,2-diacyl-sn-glycerol 3-phosphate (phosphatidic acid) for the synthesis of phosphatidylinositols Drosophila melanogaster
2.7.1.107 physiological function DGKs broadly regulate signaling events by virtue of their ability to provide 1,2-diacyl-sn-glycerol 3-phosphate (phosphatidic acid) for the synthesis of phosphatidylinositols Sus scrofa
2.7.1.107 physiological function DGKs broadly regulate signaling events by virtue of their ability to provide 1,2-diacyl-sn-glycerol 3-phosphate (phosphatidic acid) for the synthesis of phosphatidylinositols Arabidopsis thaliana
2.7.1.107 physiological function DGKs broadly regulate signaling events by virtue of their ability to provide 1,2-diacyl-sn-glycerol 3-phosphate (phosphatidic acid) for the synthesis of phosphatidylinositols Caenorhabditis elegans
2.7.1.107 physiological function DGKs broadly regulate signaling events by virtue of their ability to provide 1,2-diacyl-sn-glycerol 3-phosphate (phosphatidic acid) for the synthesis of phosphatidylinositols, isoform DGKzeta activates phosphatidylinositol-4-phosphate 5-kinase type Ialpha, DGKzeta modulates Rac1 activation to influence neurite outgrowth, DGKzeta modulates mTor activation and immune cell signaling Mus musculus