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Literature summary extracted from

  • Rashidi, M.R.; Soruraddin, M.H.; Taherzadeh, F.; Jouyban, A.
    Catalytic activity and stability of xanthine oxidase in aqueous-organic mixtures (2009), Biochemistry (Moscow), 74, 97-101.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.17.3.2 acetonitrile
-
 Bos taurus
1.17.3.2 dimethylformamide highly stimulating Bos taurus
1.17.3.2 dioxane
-
 Bos taurus
1.17.3.2 ethanol
-
 Bos taurus
1.17.3.2 methanol slightly stimulating Bos taurus
1.17.3.2 additional information the enzyme activity is stimulated by organic solvents, but the effect is reduced with increasing temperature, from 27°C to 37°C, the inhibitory effects of all organic solvents on the enzyme activity are increased at higher temperature Bos taurus
1.17.3.2 Propanol slightly stimulating Bos taurus
1.17.3.2 tetrahydrofuran
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.17.3.2 extracellular secreted to milk Bos taurus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.17.3.2 Molybdenum a molybdenum-containing enzyme Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.3.2 xanthine + O2 + H2O Bos taurus
-
 urate + H2O2
-
 ?

Organic Solvent Stability

EC Number Organic Solvent Comment Organism
1.17.3.2 additional information the enzyme activity is stimulated by organic solvents, but the effect is reduced with increasing temperature, from 27°C to 37°C, the inhibitory effects of all organic solvents on the enzyme activity are increased at higher temperature, dependent on pH, overview Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 commercial preparation
-
 Bos taurus
-
1.17.3.2 milk
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 xanthine + O2 + H2O
-
 Bos taurus urate + H2O2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.17.3.2 37
-
 assay at Bos taurus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
1.17.3.2 27 50
-
 Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.17.3.2 7
-
 assay at Bos taurus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.17.3.2 6 9
-
 Bos taurus

General Information

EC Number General Information Comment Organism
1.17.3.2 metabolism the enzyme plays an important role in the metabolism of many xenobiotics and drugs, such as purines and pyrimidines, mercaptopurine and azathioprine, thiazides, pyrazinamide, and acyclovir Bos taurus
1.17.3.2 additional information the enzyme also serves as an important biological source of reactive oxygen species that are involved in many pathological processes, such as inflammation, atherosclerosis, cancer, and aging Bos taurus