EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.4 | Prostaglandin H2 | Mus musculus | - |
Prostaglandin I2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.4 | Mus musculus | - |
- |
- |
5.3.99.5 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
5.3.99.4 | aorta | atherosclerotic aorta | Mus musculus | - |
5.3.99.5 | aorta | atherosclerotic aorta | Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.4 | Prostaglandin H2 | - |
Mus musculus | Prostaglandin I2 | - |
? | |
5.3.99.5 | prostaglandin H2 | - |
Mus musculus | thromboxane A2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.4 | PGIS | - |
Mus musculus |
5.3.99.4 | prostacyclin synthase | - |
Mus musculus |
5.3.99.5 | TXAS | - |
Mus musculus |
EC Number | Organism | Comment | Expression |
---|---|---|---|
5.3.99.4 | Mus musculus | after 16 weeks the prostacyclin synthase mRNA levels are reduced | down |
5.3.99.4 | Mus musculus | after 8 weeks on fat diet, aortic arches from low-density lipoprotein receptor deficient, LDL r-KO, mice shows a significant increase in prostacyclin synthase levels | up |
5.3.99.5 | Mus musculus | after 8 and 16 weeks on the fat diet, aortic arches from low-density lipoprotein receptor deficient mice show a significant increase in TXAS mRNA level when compared with control | up |