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Literature summary extracted from

  • Trabelsi, N.; Petit, P.; Manigand, C.; Langlois d'Estaintot, B.; Granier, T.; Chaudiere, J.; Gallois, B.
    Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols (2008), Acta Crystallogr. Sect. D, 64, 883-891.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.219 DFR-NADP+-flavonol (myricetin and quercetin) complexes, at room temperature, by hanging-drop vapour diffusion method. Complex DFR-NADP+-myricetin belongs to space group P21 (unit-cell parameters a = 47.23, b = 177.96, c = 92.60 A, beta = 104.8°). Complex DFR-NADP+-quercetin belongs to space group P6122 (unit-cell parameters a = b = 174.94, c = 290.18 A) Vitis vinifera

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.219 myricetin flavonol that can be an inhibitor of the activity of DFR towards dihydroflavonols Vitis vinifera
1.1.1.219 quercetin flavonol that can be an inhibitor of the activity of DFR towards dihydroflavonols Vitis vinifera

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.219 Vitis vinifera
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.219 dihydroquercetin + NADPH + H+
-
Vitis vinifera leucocyanidin + NADP+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.219 DFR
-
Vitis vinifera
1.1.1.219 dihydroflavonol 4-reductase
-
Vitis vinifera

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.219 NADP+
-
Vitis vinifera