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Literature summary extracted from

  • Zhong, S.R.; Jin, Y.; Wu, J.B.; Jia, Y.H.; Xu, G.L.; Wang, G.C.; Xiong, Y.L.; Lu, Q.M.
    Purification and characterization of a new L-amino acid oxidase from Daboia russellii siamensis venom (2009), Toxicon, 54, 763-771.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.2 extracellular venom Daboia siamensis
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.2 58000
-
 2 * 58000, SDS-PAGE Daboia siamensis
1.4.3.2 120000
-
 gel filtration Daboia siamensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.3.2 additional information Daboia siamensis LAAO dose-dependently inhibits platelet aggregation and exhibits antibactericidal activity ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.2 Daboia siamensis Q4F867
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.2 native enzyme by anion exchange chromatography, gel filtration, and heparin affinity chromatography to homogeneity Daboia siamensis

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.2 venom
-
 Daboia siamensis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.2 L-Ile + H2O + O2
-
 Daboia siamensis 3-methyl-2-oxopentanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Daboia siamensis 4-methyl-2-oxopentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Daboia siamensis phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 additional information LAAO dose-dependently inhibits platelet aggregation and exhibits antibactericidal activity Daboia siamensis ?
-
 ?
1.4.3.2 additional information substrate specificity, overview. No activity with L-Pro, L-Asn, Gly, L-Ser, and L-Cys. The enzyme shows no hemorrhagic activity Daboia siamensis ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.2 homodimer 2 * 58000, SDS-PAGE Daboia siamensis

Synonyms

EC Number Synonyms Comment Organism
1.4.3.2 LAAO
-
 Daboia siamensis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.4.3.2 25
-
 assay at Daboia siamensis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.3.2 8.8
-
-
 Daboia siamensis