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Literature summary extracted from

  • Garcia, D.G.; Bianco, E.M.; Santos, M.D.; Pereira, R.C.; Faria, M.V.; Teixeira, V.L.; Burth, P.
    Inhibition of mammal Na(+)K(+)-ATPase by diterpenes extracted from the Brazilian brown alga Dictyota cervicornis (2009), Phytother. Res., 23, 943-947.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.13 4,7-diacetoxy-14-hydroxydolast-1(15),8-diene
-
 Cavia porcellus
7.2.2.13 4-acetoxy-9,14-dihydroxydolast-1(15),7-diene
-
 Cavia porcellus
7.2.2.13 oleic acid
-
 Cavia porcellus
7.2.2.13 Ouabain
-
 Cavia porcellus

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.13 Cavia porcellus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.2.2.13
-
 Cavia porcellus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.13 brain mainly alpha2- and alpha3 isoform Cavia porcellus
-
7.2.2.13 kidney alpha1-isoform Cavia porcellus
-

Synonyms

EC Number Synonyms Comment Organism
7.2.2.13 Na+-K+-ATPase
-
 Cavia porcellus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
7.2.2.13 0.0016
-
 enzym preparation from kidney Cavia porcellus Ouabain
7.2.2.13 0.115
-
 enzym preparation from kidney Cavia porcellus oleic acid
7.2.2.13 0.171
-
 enzym preparation from kidney Cavia porcellus 4,7-diacetoxy-14-hydroxydolast-1(15),8-diene