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Literature summary extracted from
- Cysteine peptidases in Herpetomonas samuelpessoai are modulated by temperature and dimethylsulfoxide-triggered differentiation (2009), Parasitology, 136, 45-54.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.B5 | leupeptin | 1 microM | Herpetomonas pessoai |  |
| 3.4.22.B5 | leupeptin | 1 microM | Leishmania amazonensis | |
| 3.4.22.B5 | trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane | 1 microM | Herpetomonas pessoai | |
| 3.4.22.B5 | trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane | 1 microM | Leishmania amazonensis | |
| 3.4.22.51 | leupeptin | 1 microM | Trypanosoma cruzi | |
| 3.4.22.51 | trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane | 1 microM | Trypanosoma cruzi | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.22.B5 | 35000 | - |
SDS-PAGE | Leishmania amazonensis |
| 3.4.22.B5 | 45000 | - |
SDS-PAGE | Herpetomonas pessoai |
| 3.4.22.B5 | 50000 | - |
SDS-PAGE, unstable | Herpetomonas pessoai |
| 3.4.24.15 | 66000 | - |
SDS-PAGE | Herpetomonas pessoai |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.B5 | Herpetomonas pessoai | - |
CT-IOC-067 | - |
| 3.4.22.B5 | Herpetomonas pessoai CT-IOC-067 | - |
CT-IOC-067 | - |
| 3.4.22.B5 | Leishmania amazonensis | - |
strain MHOM/BR/75 Josefa | - |
| 3.4.22.B5 | Leishmania amazonensis MHOM/BR/75/Josefa | - |
strain MHOM/BR/75 Josefa | - |
| 3.4.22.51 | Trypanosoma cruzi | - |
- |
- |
| 3.4.22.51 | Trypanosoma cruzi Dm28c | - |
- |
- |
| 3.4.24.15 | Herpetomonas pessoai | - |
- |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.22.B5 | cpb-like | - |
Herpetomonas pessoai |
| 3.4.22.B5 | cysteine peptidase | - |
Herpetomonas pessoai |
| 3.4.22.B5 | cysteine peptidase B | - |
Leishmania amazonensis |
| 3.4.22.51 | cruzipain | - |
Trypanosoma cruzi |
| 3.4.24.15 | metallopeptidase | - |
Herpetomonas pessoai |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.22.B5 | 26 | - |
reduced activity at 37 °C | Herpetomonas pessoai |
Temperature Range [°C]
| EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.15 | 26 | 37 | - |
Herpetomonas pessoai |
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