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Literature summary extracted from

  • Wild, J.; Klopotowski, T.
    D-Amino acid dehydrogenase of Escherichia coli K12: positive selection of mutants defective in enzyme activity and localization of the structural gene (1981), Mol. Gen. Genet., 181, 373-378.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.5.1 membrane enzyme activity depends on membrane integrity Escherichia coli K-12 16020
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.5.1 D-alanine + oxidized acceptor + H2O Escherichia coli K-12 the enzyme is inducible by L-alanine and repressible by glucose pyruvate + NH3 + reduced acceptor
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.5.1 Escherichia coli K-12
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.5.1 beta-chloro-D-alanine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 20% of the activity with D-alanine Escherichia coli K-12 ? + NH3 + reduced acceptor
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 ?
1.4.5.1 D-alanine + oxidized acceptor + H2O the enzyme is inducible by L-alanine and repressible by glucose Escherichia coli K-12 pyruvate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-alanine + oxidized acceptor + H2O assayed in toluenized cells, formation of pyruvate is determined using 2,4-dinitrophenylhydrazine Escherichia coli K-12 pyruvate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-arginine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 2.9% of the activity with D-alanine Escherichia coli K-12 2-oxo-5-guanidinopentanoate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-asparagine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 21% of the activity with D-alanine Escherichia coli K-12 2-oxosuccinamic acid + NH3 + reduced acceptor
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 ?
1.4.5.1 D-cysteine + oxidized acceptor assayed in toluenized cells, reaction rate is 4.1% of the activity with D-alanine Escherichia coli K-12 ? + NH3 + reduced acceptor
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 ?
1.4.5.1 D-ethionine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 41% of the activity with D-alanine Escherichia coli K-12 ? + NH3 + reduced acceptor
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 ?
1.4.5.1 D-histidine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 12% of the activity with D-alanine Escherichia coli K-12 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-leucine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 20% of the activity with D-alanine Escherichia coli K-12 4-methyl-2-oxopentanoate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-methionine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 39% of the activity with D-alanine Escherichia coli K-12 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-phenylalanine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 72% of the activity with D-alanine Escherichia coli K-12 phenylpyruvate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-proline + oxidized acceptor assayed in toluenized cells, reaction rate is 2.6% of the activity with D-alanine Escherichia coli K-12 DELTA1-pyrroline-2-carboxylate + reduced acceptor
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 ?
1.4.5.1 D-serine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 13% of the activity with D-alanine Escherichia coli K-12 3-hydroxy-2-oxopropanoate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-threonine + H2O + oxidized acceptor assayed in toluenized cells, reaction rate is 5.9% of the activity with D-alanine Escherichia coli K-12 3-hydroxy-2-oxobutanoate + NH3 + reduced acceptor
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 ?
1.4.5.1 D-valine + oxidized acceptor + H2O assayed in toluenized cells, reaction rate is 2.6% of the activity with D-alanine Escherichia coli K-12 2-oxoisopentanoate + NH3 + reduced acceptor
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 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.5.1 DadA
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 Escherichia coli K-12