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Literature summary extracted from

  • Tojo, Y.; Hamase, K.; Konno, R.; Koyanagi, S.; Ohdo, S.; Zaitsu, K.
    Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis (2009), J. Sep. Sci., 32, 430-436.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.4.3.3 analysis genotyping method development for establishing various pathologic-model animals under the complete care of their intrinsic DAO activity, which are useful for the screening of D-amino acids having physiological activity and/or diagnostic value Mus musculus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.4.3.3 simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis, method development, overview. Verification of the genotyping method by the crossbreeding of DAO+/+ and DAO-/- mice Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.3.3 D-alanine + H2O + O2 Mus musculus
-
 pyruvate + NH3 + H2O2
-
 ?
1.4.3.3 additional information Mus musculus DAO catalyzes the oxidative degradation of most of the D-amino acids in mammals ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.3 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.4.3.3 flavoprotein
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.3 kidney
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.3 D-alanine + H2O + O2
-
 Mus musculus pyruvate + NH3 + H2O2
-
 ?
1.4.3.3 additional information DAO catalyzes the oxidative degradation of most of the D-amino acids in mammals Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.3 DAO
-
 Mus musculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.4.3.3 37
-
 assay at Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.3.3 8.3
-
 assay at Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.3 flavin flavoenzyme Mus musculus