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Literature summary extracted from

  • Bevers, M.B.; Lawrence, E.; Maronski, M.; Starr, N.; Amesquita, M.; Neumar, R.W.
    Knockdown of m-calpain increases survival of primary hippocampal neurons following NMDA excitotoxicity (2009), J. Neurochem., 108, 1237-1250.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.52 additional information specific capn1 shRNA reduces expression of the targeted isoform Rattus norvegicus
3.4.22.52 Z-Val-Phe-CHO i.e. MDL-28710, 1.0 microM Rattus norvegicus
3.4.22.53 additional information specific capn2 shRNA reduces expression of the targeted isoform Rattus norvegicus
3.4.22.53 Z-Val-Phe-CHO i.e. MDL-28710m, 1.0 microM Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.52 Rattus norvegicus
-
-
-
3.4.22.53 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.52 fibroblast
-
 Rattus norvegicus
-
3.4.22.53 fibroblast
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.52 AIF + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.52 collapsin response mediator protein 1 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.52 collapsin response mediator protein 2 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.52 collapsin response mediator protein 3 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.52 collapsin response mediator protein 4 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.52 cyclin dependent kinase-5 + H2O
-
 Rattus norvegicus p25-CDK5
-
 ?
3.4.22.53 AIF + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.53 collapsin response mediator protein 1 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.53 collapsin response mediator protein 2 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.53 collapsin response mediator protein 3 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.53 collapsin response mediator protein 4 + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.22.53 cyclin dependent kinase-5 + H2O
-
 Rattus norvegicus p25-CDK5
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.22.52 calpain 1
-
 Rattus norvegicus
3.4.22.52 CAPN2
-
 Rattus norvegicus
3.4.22.52 cysteine protease
-
 Rattus norvegicus
3.4.22.52 micro-calpain
-
 Rattus norvegicus
3.4.22.53 calpain 2
-
 Rattus norvegicus
3.4.22.53 CAPN2
-
 Rattus norvegicus
3.4.22.53 cysteine protease
-
 Rattus norvegicus
3.4.22.53 m-calpain
-
 Rattus norvegicus