EC Number | Application | Comment | Organism |
---|---|---|---|
1.1.1.35 | medicine | HADH protects against excess amino acid-induced insulin secretion | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.35 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.35 | leukocyte | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.35 | 3-oxohexadecanoyl-CoA + NADH + H+ | - |
Homo sapiens | (S)-3-hydroxhexadecanoyl-CoA + NAD+ | - |
? | |
1.1.1.35 | 3-oxooctanoyl-CoA + NADH + H+ | - |
Homo sapiens | (S)-3-hydroxyoctanoyl-CoA + NAD+ | - |
? | |
1.1.1.35 | acetoacetyl-CoA + NADH + H+ | - |
Homo sapiens | 3-hydroxybutyryl-CoA + NAD+ | - |
? | |
1.1.1.35 | additional information | HADH gene with a novel homozygous missense mutation M188V. Mutations in the HADH gene are associated with significantly decreased short-chain L-HADH activity, mildly decreased medium- and long-chain L-HADH activity, protein-induced hyperinsulinemic hypoglycemia. Patients with hyperinsulinemic hypoglycemia due to HADH gene mutations may have normal acylcarnitines and urine organic acids | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.35 | 3-hydroxyacyl-coenzyme A dehydrogenase | - |
Homo sapiens |
1.1.1.35 | HADH | - |
Homo sapiens |