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Literature summary extracted from

  • Yin, J.; Lu, J.; Yu, F.S.
    Role of small GTPase Rho in regulating corneal epithelial wound healing (2008), Invest. Ophthalmol. Vis. Sci., 49, 900-909.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.5.2 heparin-binding epidermal growth factor-like growth factor induces rapid and strong RhoA activation Homo sapiens
3.6.5.2 heparin-binding epidermal growth factor-like growth factor induces rapid and strong RhoA activation Sus scrofa
3.6.5.2 lysophosphatidic acid induces rapid and strong RhoA activation Homo sapiens
3.6.5.2 lysophosphatidic acid induces rapid and strong RhoA activation Sus scrofa
3.6.5.2 additional information wounding induces rapid and strong RhoA activation Homo sapiens
3.6.5.2 additional information wounding induces rapid and strong RhoA activation Sus scrofa

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.6.5.2 expressed in Escherichia coli BL21 cells Homo sapiens
3.6.5.2 expressed in Escherichia coli BL21 cells Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.5.2 Clostridium botulinum exoenzyme C3 specific inhibitor Homo sapiens
3.6.5.2 Clostridium botulinum exoenzyme C3 specific inhibitor Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.5.2 additional information Homo sapiens RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding ?
-
 ?
3.6.5.2 additional information Sus scrofa RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.5.2 Homo sapiens
-
-
-
3.6.5.2 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.5.2 corneal epithelial cell
-
 Homo sapiens
-
3.6.5.2 corneal epithelial cell
-
 Sus scrofa
-
3.6.5.2 THCE cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.5.2 additional information RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding Homo sapiens ?
-
 ?
3.6.5.2 additional information RhoA activity is required for modulating cell migration and proliferation through cytoskeleton reorganization and focal adhesion formation in response to wounding Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.5.2 Rho
-
 Homo sapiens
3.6.5.2 Rho
-
 Sus scrofa
3.6.5.2 RhoA
-
 Homo sapiens
3.6.5.2 RhoA
-
 Sus scrofa