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Literature summary extracted from

  • Enami, Y.; Bandi, S.; Kapoor, S.; Krohn, N.; Joseph, B.; Gupta, S.
    Hepatic stellate cells promote hepatocyte engraftment in rat liver after prostaglandin-endoperoxide synthase inhibition (2009), Gastroenterology, 136, 2356-2364.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.99.1 celecoxib
-
 Rattus norvegicus
1.14.99.1 naproxen
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.1 Rattus norvegicus P35355
-
-
1.14.99.1 Rattus norvegicus Q63921
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.99.1 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.1 arachidonate + AH2 + O2
-
 Rattus norvegicus prostaglandin H2 + A + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.99.1 prostaglandin-endoperoxide synthase 1 isoform Rattus norvegicus
1.14.99.1 prostaglandin-endoperoxide synthase 2 isoform Rattus norvegicus
1.14.99.1 PTGS1 isoform Rattus norvegicus
1.14.99.1 PTGS2 isoform Rattus norvegicus

Expression

EC Number Organism Comment Expression
1.14.99.1 Rattus norvegicus transplantation of hepatocytes induces hepatic expression of prostaglandin-endoperoxide synthase isoform 1 (5fold) up
1.14.99.1 Rattus norvegicus transplantation of hepatocytes induces hepatic expression of prostaglandin-endoperoxide synthase isoform 2 (2.8fold) up