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Literature summary extracted from
- Changes in quinic acid metabolism during fruit development in three kiwifruit species (2009), Funct. Plant Biol., 36, 463-470.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.24 | 0.3 | - |
quinic acid | purification step Q1 HiTrapQ, cofactor NAD+ | Actinidia deliciosa |  |
| 1.1.1.24 | 0.3 | - |
quinic acid | purification step Q2 HiTrapQ, cofactor NADP+ | Actinidia deliciosa | |
| 1.1.1.24 | 0.5 | - |
quinic acid | purification step Q1 HiTrapQ, cofactor NADP+ | Actinidia deliciosa | |
| 1.1.1.24 | 0.8 | - |
quinic acid | purification step unbound to HiTrapQ, cofactor NADP+ | Actinidia deliciosa | |
| 1.1.1.24 | 1.9 | - |
quinic acid | purification step Q2 HiTrapQ, cofactor NAD+ | Actinidia deliciosa | |
| 1.1.1.24 | 10.9 | - |
quinic acid | purification step unbound to HiTrapQ, cofactor NAD+ | Actinidia deliciosa | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.24 | quinic acid + NAD(P)+ | Actinidia chinensis | - |
dehydroquinic acid + NAD(P)H + H+ | - |
r | |
| 1.1.1.24 | quinic acid + NAD(P)+ | Actinidia deliciosa | - |
dehydroquinic acid + NAD(P)H + H+ | - |
r | |
| 1.1.1.24 | quinic acid + NAD(P)+ | Actinidia arguta | - |
dehydroquinic acid + NAD(P)H + H+ | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.24 | Actinidia arguta | - |
- |
- |
| 1.1.1.24 | Actinidia arguta var. arguta | - |
- |
- |
| 1.1.1.24 | Actinidia chinensis | - |
- |
- |
| 1.1.1.24 | Actinidia deliciosa | - |
- |
- |
| 1.1.1.24 | Actinidia deliciosa var. deliciosa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.24 | partial from young kiwifruit by extraction and chromatography on Superdex G75 and HiTrapQ columns | Actinidia deliciosa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.24 | fruit | - |
Actinidia chinensis | - |
| 1.1.1.24 | fruit | - |
Actinidia deliciosa | - |
| 1.1.1.24 | fruit | - |
Actinidia arguta | - |
| 1.1.1.24 | fruit | quinate dehydrogenase activity is at a maximum around the time of greatest quinic acid accumulation in the early stages (less than 60 days after anthesis) of fruit development. It declines markedly in late fruit development | Actinidia arguta var. arguta | - |
| 1.1.1.24 | fruit | quinate dehydrogenase activity is at a maximum around the time of greatest quinic acid accumulation in the early stages (less than 60 days after anthesis) of fruit development. It declines markedly in late fruit development, and is higher in species that accumulate the largest amounts of quinic acid (Actinidia chinensis and Actinidia deliciosa) | Actinidia chinensis | - |
| 1.1.1.24 | fruit | quinate dehydrogenase activity is at a maximum around the time of greatest quinic acid accumulation in the early stages (less than 60 days after anthesis) of fruit development. It declines markedly in late fruit development, and is higher in species that accumulate the largest amounts of quinic acid (Actinidia chinensis and Actinidia deliciosa) | Actinidia deliciosa var. deliciosa | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.24 | additional information | - |
quinate dehydrogenase activity is highest early in fruit development abd declines in older fruit | Actinidia chinensis |
| 1.1.1.24 | additional information | - |
quinate dehydrogenase activity is highest early in fruit development abd declines in older fruit | Actinidia arguta |
| 1.1.1.24 | additional information | - |
quinate dehydrogenase activity is highest early in fruit development and declines in older fruit | Actinidia deliciosa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.24 | quinic acid + NAD(P)+ | - |
Actinidia chinensis | dehydroquinic acid + NAD(P)H + H+ | - |
r | |
| 1.1.1.24 | quinic acid + NAD(P)+ | - |
Actinidia deliciosa | dehydroquinic acid + NAD(P)H + H+ | - |
r | |
| 1.1.1.24 | quinic acid + NAD(P)+ | - |
Actinidia arguta | dehydroquinic acid + NAD(P)H + H+ | - |
r | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.1.24 | QDH | - |
Actinidia chinensis |
| 1.1.1.24 | QDH | - |
Actinidia deliciosa |
| 1.1.1.24 | QDH | - |
Actinidia deliciosa var. deliciosa |
| 1.1.1.24 | QDH | - |
Actinidia arguta var. arguta |
| 1.1.1.24 | QDH | - |
Actinidia arguta |
| 1.1.1.24 | quinate dehydrogenase | - |
Actinidia chinensis |
| 1.1.1.24 | quinate dehydrogenase | - |
Actinidia deliciosa |
| 1.1.1.24 | quinate dehydrogenase | - |
Actinidia arguta |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.24 | 10 | - |
activity assay | Actinidia chinensis |
| 1.1.1.24 | 10 | - |
activity assay | Actinidia deliciosa |
| 1.1.1.24 | 10 | - |
activity assay | Actinidia arguta |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.24 | NAD+ | - |
Actinidia chinensis | |
| 1.1.1.24 | NAD+ | - |
Actinidia deliciosa | |
| 1.1.1.24 | NAD+ | - |
Actinidia arguta | |
| 1.1.1.24 | NADP+ | - |
Actinidia chinensis | |
| 1.1.1.24 | NADP+ | - |
Actinidia deliciosa | |
| 1.1.1.24 | NADP+ | - |
Actinidia arguta | |
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Release 2023.1 (January 2023)
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