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Literature summary extracted from
- Activities of gamma-butyrobetaine dioxygenase and concentrations of carnitine in tissues of pigs (2009), Comp. Biochem. Physiol. A, 153, 324-331.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.11.1 | Sus scrofa | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.11.1 | blood | - |
Sus scrofa | - |
| 1.14.11.1 | brain | - |
Sus scrofa | - |
| 1.14.11.1 | colon | - |
Sus scrofa | - |
| 1.14.11.1 | duodenum | - |
Sus scrofa | - |
| 1.14.11.1 | epididymis | - |
Sus scrofa | - |
| 1.14.11.1 | heart | - |
Sus scrofa | - |
| 1.14.11.1 | kidney | - |
Sus scrofa | - |
| 1.14.11.1 | liver | - |
Sus scrofa | - |
| 1.14.11.1 | longissimus | - |
Sus scrofa | - |
| 1.14.11.1 | lung | - |
Sus scrofa | - |
| 1.14.11.1 | plasma | - |
Sus scrofa | - |
| 1.14.11.1 | semimembranosus | - |
Sus scrofa | - |
| 1.14.11.1 | spleen | - |
Sus scrofa | - |
| 1.14.11.1 | testis | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.14.11.1 | additional information | - |
value below 0.00001 mM in skeletal muscle, heart, colon, lung, spleen | Sus scrofa |
| 1.14.11.1 | 0.0004 | - |
activity of gamma-butyrobetaine dioxygenase in liver | Sus scrofa |
| 1.14.11.1 | 0.0024 | - |
activity of gamma-butyrobetaine dioxygenase in kidney | Sus scrofa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.11.1 | gamma-butyrobetaine + 2-oxoglutarate + O2 | - |
Sus scrofa | carnitine + succinate + CO2 | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.11.1 | BBD | - |
Sus scrofa |
| 1.14.11.1 | gamma-butyrobetaine dioxygenase | - |
Sus scrofa |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.14.11.1 | Sus scrofa | highest mRNA concentrations in epididymis and in kidney. In heart, colon, small intestine, lung, spleen, testes and brain lower mRNA levels compared to liver. In skeletal muscle almost absent mRNA amount | additional information |
| 1.14.11.1 | Sus scrofa | activity of gamma-butyrobetaine dioxygenase lowest at birth in liver and kidney, but increase until age of 2 weeks | up |
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Release 2023.1 (January 2023)
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