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Literature summary extracted from
- Carbonylation of platelet proteins occurs as consequence of oxidative stress and thrombin activation, and is stimulated by ageing and type 2 diabetes (2008), Clin. Chem. Lab. Med., 46, 528-536.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.21.5 | medicine | exogenous oxidative stress, thrombin activation, progression of ageing and type 2 diabetes lead to protein carbonyls formation in platelets, and this modification can be attenuated by antioxidant enzymes | Homo sapiens |
| 3.4.21.5 | medicine | exogenous oxidative stress, thrombin activation, progression of ageing and type 2 diabetes lead to protein carbonyls formation in platelets, and this modification can be attenuated by antioxidant enzymes | Rattus norvegicus |
| 3.4.21.5 | medicine | exogenous oxidative stress, thrombin activation, progression of ageing and type 2 diabetes lead to protein carbonyls formation in platelets, and this modification can be attenuated by antioxidant enzymes | Mesocricetus auratus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.5 | Homo sapiens | - |
- |
- |
| 3.4.21.5 | Mesocricetus auratus | - |
- |
- |
| 3.4.21.5 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.5 | blood platelet | exogenous oxidative stress, thrombin activation, progression of ageing and type 2 diabetes lead to protein carbonyls formation in platelets, and this modification can be attenuated by antioxidant enzymes | Homo sapiens | - |
| 3.4.21.5 | blood platelet | exogenous oxidative stress, thrombin activation, progression of ageing and type 2 diabetes lead to protein carbonyls formation in platelets, and this modification can be attenuated by antioxidant enzymes | Rattus norvegicus | - |
| 3.4.21.5 | blood platelet | exogenous oxidative stress, thrombin activation, progression of ageing and type 2 diabetes lead to protein carbonyls formation in platelets, and this modification can be attenuated by antioxidant enzymes | Mesocricetus auratus | - |
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Release 2023.1 (January 2023)
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