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Literature summary extracted from

  • Poulsen, L.R.; Lopez-Marques, R.L.; Palmgren, M.G.
    Flippases: still more questions than answers (2008), Cell. Mol. Life Sci., 65, 3119-3125.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.6.2.1 additional information Lem3p interacts and sustains functionality of isozymes Dnf1p and Dnf2p Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.6.2.1 Golgi apparatus isoform Drs2p Saccharomyces cerevisiae 5794
-
7.6.2.1 membrane
-
 Saccharomyces cerevisiae 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.6.2.1 additional information Saccharomyces cerevisiae isozyme Drs2p interacts with the guanine nucleotide exchange factor Gea2p involved in activation of ADP-ribosylation factors ?
-
 ?
7.6.2.1 additional information Saccharomyces cerevisiae isozyme Neo1p interacts with the guanine nucleotide exchange factor Ysl2p/Mon2p and the Arf Arl1p, and cooperation between these three proteins is important for recruitment of clathrin adaptors ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.1 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.1 ATP + H2O + phosphatidylethanolamine/out
-
 Saccharomyces cerevisiae ADP + phosphate + phosphatidylethanolamine/in
-
 ?
7.6.2.1 ATP + H2O + phosphatidylserine/out
-
 Saccharomyces cerevisiae ADP + phosphate + phosphatidylserine/in
-
 ?
7.6.2.1 additional information isozyme Drs2p interacts with the guanine nucleotide exchange factor Gea2p involved in activation of ADP-ribosylation factors Saccharomyces cerevisiae ?
-
 ?
7.6.2.1 additional information isozyme Neo1p interacts with the guanine nucleotide exchange factor Ysl2p/Mon2p and the Arf Arl1p, and cooperation between these three proteins is important for recruitment of clathrin adaptors Saccharomyces cerevisiae ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.6.2.1 Dnf1p isoform Saccharomyces cerevisiae
7.6.2.1 Dnf2p isoform Saccharomyces cerevisiae
7.6.2.1 Dnf3p isoform Saccharomyces cerevisiae
7.6.2.1 Drs2p isoform Saccharomyces cerevisiae
7.6.2.1 flippase
-
 Saccharomyces cerevisiae
7.6.2.1 Neo1p isoform Saccharomyces cerevisiae