BRENDA - Enzyme Database

Flippases: still more questions than answers

Poulsen, L.R.; Lopez-Marques, R.L.; Palmgren, M.G.; Cell. Mol. Life Sci. 65, 3119-3125 (2008)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
7.6.2.1
additional information
Lem3p interacts and sustains functionality of isozymes Dnf1p and Dnf2p
Saccharomyces cerevisiae
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
7.6.2.1
Golgi apparatus
isoform Drs2p
Saccharomyces cerevisiae
5794
-
7.6.2.1
membrane
-
Saccharomyces cerevisiae
16020
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
7.6.2.1
additional information
Saccharomyces cerevisiae
isozyme Drs2p interacts with the guanine nucleotide exchange factor Gea2p involved in activation of ADP-ribosylation factors
?
-
-
-
7.6.2.1
additional information
Saccharomyces cerevisiae
isozyme Neo1p interacts with the guanine nucleotide exchange factor Ysl2p/Mon2p and the Arf Arl1p, and cooperation between these three proteins is important for recruitment of clathrin adaptors
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
7.6.2.1
Saccharomyces cerevisiae
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
7.6.2.1
ATP + H2O + phosphatidylethanolamine/out
-
697213
Saccharomyces cerevisiae
ADP + phosphate + phosphatidylethanolamine/in
-
-
-
?
7.6.2.1
ATP + H2O + phosphatidylserine/out
-
697213
Saccharomyces cerevisiae
ADP + phosphate + phosphatidylserine/in
-
-
-
?
7.6.2.1
additional information
isozyme Drs2p interacts with the guanine nucleotide exchange factor Gea2p involved in activation of ADP-ribosylation factors
697213
Saccharomyces cerevisiae
?
-
-
-
-
7.6.2.1
additional information
isozyme Neo1p interacts with the guanine nucleotide exchange factor Ysl2p/Mon2p and the Arf Arl1p, and cooperation between these three proteins is important for recruitment of clathrin adaptors
697213
Saccharomyces cerevisiae
?
-
-
-
-
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
7.6.2.1
additional information
Lem3p interacts and sustains functionality of isozymes Dnf1p and Dnf2p
Saccharomyces cerevisiae
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
7.6.2.1
Golgi apparatus
isoform Drs2p
Saccharomyces cerevisiae
5794
-
7.6.2.1
membrane
-
Saccharomyces cerevisiae
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
7.6.2.1
additional information
Saccharomyces cerevisiae
isozyme Drs2p interacts with the guanine nucleotide exchange factor Gea2p involved in activation of ADP-ribosylation factors
?
-
-
-
7.6.2.1
additional information
Saccharomyces cerevisiae
isozyme Neo1p interacts with the guanine nucleotide exchange factor Ysl2p/Mon2p and the Arf Arl1p, and cooperation between these three proteins is important for recruitment of clathrin adaptors
?
-
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
7.6.2.1
ATP + H2O + phosphatidylethanolamine/out
-
697213
Saccharomyces cerevisiae
ADP + phosphate + phosphatidylethanolamine/in
-
-
-
?
7.6.2.1
ATP + H2O + phosphatidylserine/out
-
697213
Saccharomyces cerevisiae
ADP + phosphate + phosphatidylserine/in
-
-
-
?
7.6.2.1
additional information
isozyme Drs2p interacts with the guanine nucleotide exchange factor Gea2p involved in activation of ADP-ribosylation factors
697213
Saccharomyces cerevisiae
?
-
-
-
-
7.6.2.1
additional information
isozyme Neo1p interacts with the guanine nucleotide exchange factor Ysl2p/Mon2p and the Arf Arl1p, and cooperation between these three proteins is important for recruitment of clathrin adaptors
697213
Saccharomyces cerevisiae
?
-
-
-
-