Any feedback?
Literature summary extracted from
- Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines (2008), Bioorg. Med. Chem. Lett., 18, 4303-4307.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.1 | 1-(2-aminoethyl)-piperazine | - |
Homo sapiens |  |
| 4.2.1.1 | 2-(2-aminoethyl)pyridine | - |
Homo sapiens | |
| 4.2.1.1 | 2-pyridyl-methylamine | - |
Homo sapiens | |
| 4.2.1.1 | 4-(2-aminoethyl)-morpholine | carbonic anhydrase IV is efficiently activated by 4-(2-aminoethyl)-morpholine | Homo sapiens | |
| 4.2.1.1 | 4-amino-L-phenylalanine | carbonic anhydrase IV is efficiently activated by 4-amino-L-phenylalanine | Homo sapiens | |
| 4.2.1.1 | aminoethyl-piperazine/morpholine | carbonic anhydrase III is efficiently activated by aminoethyl-piperazine/morpholine | Homo sapiens | |
| 4.2.1.1 | D-Dopa | - |
Homo sapiens | |
| 4.2.1.1 | D-His | carbonic anhydrase III is efficiently activated by D-His | Homo sapiens | |
| 4.2.1.1 | D-Phe | - |
Homo sapiens | |
| 4.2.1.1 | D-Trp | - |
Homo sapiens | |
| 4.2.1.1 | dopamine | - |
Homo sapiens | |
| 4.2.1.1 | histamine | - |
Homo sapiens | |
| 4.2.1.1 | L-adrenaline | - |
Homo sapiens | |
| 4.2.1.1 | L-Dopa | - |
Homo sapiens | |
| 4.2.1.1 | L-His | - |
Homo sapiens | |
| 4.2.1.1 | L-Phe | - |
Homo sapiens | |
| 4.2.1.1 | L-Trp | - |
Homo sapiens | |
| 4.2.1.1 | L-Tyr | - |
Homo sapiens | |
| 4.2.1.1 | serotonin | carbonic anhydrases III and IV are efficiently activated by serotinin | Homo sapiens | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.2.1.1 | cytosol | isozyme carbonic anhydrase III | Homo sapiens | 5829 | - |
| 4.2.1.1 | membrane | isozyme carbonic anhydrase IV | Homo sapiens | 16020 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.1 | Homo sapiens | - |
- |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.1.1 | CA III | isozyme | Homo sapiens |
| 4.2.1.1 | CA IV | isozyme | Homo sapiens |
| 4.2.1.1 | carbonic anhydrase III | isozyme | Homo sapiens |
| 4.2.1.1 | carbonic anhydrase IV | isozyme | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
