EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.7 | dantrolene | non-competitive inhibition | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.7 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.1.7 | ammonium sulfate precipitation, 2 ',5'-ADP Sepharose-4B affinity column chromatography and Sephadex G-200 gel filtration | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.8.1.7 | erythrocyte | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.8.1.7 | 0.009 | - |
hemolysate, at 25°C, pH 8.0 | Homo sapiens |
1.8.1.7 | 23 | - |
2555fold purified enzyme, at 25°C, pH 8.0 | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.7 | glutathione disulfide + NADPH + H+ | - |
Homo sapiens | glutathione + NADP+ | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.7 | glutathione reductase | - |
Homo sapiens |
1.8.1.7 | glutathione: NADP+ oxidoreductase | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.7 | FAD | - |
Homo sapiens | |
1.8.1.7 | NADPH | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.8.1.7 | 0.1116 | - |
dantrolene | at 25°C, pH 8.0 | Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.8.1.7 | 0.0523 | - |
at 25°C, pH 8.0 | Homo sapiens | dantrolene |