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Literature summary extracted from

  • Kovacevic, Z.; Fu, D.; Richardson, D.R.
    The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets (2008), Biochim. Biophys. Acta, 1783, 1981-1992.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.1.28 additional information overexpression of N-myc downstream regulated gene-1, Ndrg-1, leads to upregulation of Thtpa in cancer cells, overview Homo sapiens
3.6.1.28 additional information overexpression of N-myc downstream regulated gene-1, Ndrg-1, leads to upregulation of Thtpa in cancer cells, overview Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.6.1.28 expression analysis Homo sapiens
3.6.1.28 expression analysis Rattus norvegicus

Protein Variants

EC Number Protein Variants Comment Organism
3.6.1.28 additional information overexpression of N-myc downstream regulated gene-1, Ndrg-1, leads to upregulation of Thtpa in cancer cells, overview Homo sapiens
3.6.1.28 additional information overexpression of N-myc downstream regulated gene-1, Ndrg-1, leads to upregulation of Thtpa in cancer cells, overview Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.28 additional information Homo sapiens Thtpa is known to decrease the levels of the energy currency molecule, thiamine triphosphate ?
-
?
3.6.1.28 additional information Rattus norvegicus Thtpa is known to decrease the levels of the energy currency molecule, thiamine triphosphate ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.28 Homo sapiens
-
-
-
3.6.1.28 Rattus norvegicus Q8CGV7
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.28 AT6.1 cell metastatic prostate cancer cells Rattus norvegicus
-
3.6.1.28 DLD-1 cell non-metastatic human colorectal adenocarcinoma cells Homo sapiens
-
3.6.1.28 NCI-H1299 cell metastatic lung cancer cells Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.28 additional information Thtpa is known to decrease the levels of the energy currency molecule, thiamine triphosphate Homo sapiens ?
-
?
3.6.1.28 additional information Thtpa is known to decrease the levels of the energy currency molecule, thiamine triphosphate Rattus norvegicus ?
-
?
3.6.1.28 thiamine triphosphate + H2O
-
Homo sapiens thiamine diphosphate + phosphate
-
?
3.6.1.28 thiamine triphosphate + H2O
-
Rattus norvegicus thiamine diphosphate + phosphate
-
?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.28 thiamine triphosphatase
-
Homo sapiens
3.6.1.28 thiamine triphosphatase
-
Rattus norvegicus
3.6.1.28 Thtpa
-
Homo sapiens
3.6.1.28 Thtpa
-
Rattus norvegicus