EC Number | Cloned (Comment) | Organism |
---|---|---|
1.11.1.24 | expressed in Escherichia coli BL21(DE3) cells | Mycobacterium tuberculosis |
EC Number | General Stability | Organism |
---|---|---|
1.11.1.24 | addition of 1 mM N-acetylcysteine to AhpE treated with equimolar H2O2 results in a destabilization of the dimer, leading to lower molecular weight species | Mycobacterium tuberculosis |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.11.1.24 | 19320 | - |
electrospray ionization mass spectrometry | Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.11.1.24 | Mycobacterium tuberculosis | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.11.1.24 | - |
Mycobacterium tuberculosis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.24 | H2O2 + reduced thioredoxin | - |
Mycobacterium tuberculosis | H2O + oxidized thioredoxin | - |
? | |
1.11.1.24 | peroxynitrite + reduced thioredoxin | AhpE reduces peroxynitrite 2 orders of magnitude faster than H2O2 | Mycobacterium tuberculosis | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.11.1.24 | AhpE | a 1-Cys peroxiredoxin | Mycobacterium tuberculosis |
1.11.1.24 | alkyl hydroperoxide reductase | - |
Mycobacterium tuberculosis |
1.11.1.24 | Rv2238c | - |
Mycobacterium tuberculosis |
EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|---|
1.11.1.24 | 4.5 | - |
AhpE is unstable and precipitates under low pH conditions (below pH 4.5) | Mycobacterium tuberculosis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.24 | thioredoxin | - |
Mycobacterium tuberculosis |