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Literature summary extracted from

  • Ogawa, F.; Shimizu, K.; Hara, T.; Muroi, E.; Komura, K.; Takenaka, M.; Hasegawa, M.; Fujimoto, M.; Takehara, K.; Sato, S.
    Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase A, in systemic sclerosis: association with pulmonary fibrosis and vascular damage (2010), Arch. Dermatol. Res., 302, 27-35.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.11 Homo sapiens Q9UJ68
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.4.11 serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.11 L-methionine (S)-sulfoxide + thioredoxin
-
 Homo sapiens L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.11 methionine sulfoxide reductase A
-
 Homo sapiens
1.8.4.11 MsrA
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.4.11 thioredoxin
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
1.8.4.11 Homo sapiens serum anti-MSRA levels are significantly elevated in systemic sclerosis patients with pulmonary fibrosis, cardiac involvement, or decreased total antioxidant power compared with those without them up