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Literature summary extracted from

  • Rossbach, S.; Mai, D.J.; Carter, E.L.; Sauviac, L.; Capela, D.; Bruand, C.; de Bruijn, F.J.
    Response of Sinorhizobium meliloti to elevated concentrations of cadmium and zinc (2008), Appl. Environ. Microbiol., 74, 4218-4221.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
7.2.2.21 additional information construction of mutant strains containing mini-Tn5 transposons, analysis of mutation effects on protein expression levels in presence of high concentrations of cadmium or zinc Sinorhizobium meliloti

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.21 ATP + H2O + Cd2+/in Sinorhizobium meliloti
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ADP + phosphate + Cd2+/out
-
?
7.2.2.21 additional information Sinorhizobium meliloti cadmium and zinc lead to the upregulation of genes encoded on the pSymA or pSymB plasmids, expression of the efflux pumps SMc01095, i.e. mexF1, and SMb20345 is enhanced 41fold and 4fold, respectively, overview ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.21 Sinorhizobium meliloti
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strains 2011 and 1021
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.21 ATP + H2O + Cd2+/in
-
Sinorhizobium meliloti ADP + phosphate + Cd2+/out
-
?
7.2.2.21 additional information cadmium and zinc lead to the upregulation of genes encoded on the pSymA or pSymB plasmids, expression of the efflux pumps SMc01095, i.e. mexF1, and SMb20345 is enhanced 41fold and 4fold, respectively, overview Sinorhizobium meliloti ?
-
?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.21 cation/proton antiporter proteins
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Sinorhizobium meliloti
7.2.2.21 More the enzyme belongs to the RND family Sinorhizobium meliloti

Cofactor

EC Number Cofactor Comment Organism Structure
7.2.2.21 ATP
-
Sinorhizobium meliloti