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Literature summary extracted from
- Beneficial effects of astragalus polysaccharides treatment on cardiac chymase activities and cardiomyopathy in diabetic hamsters (2010), Acta Diabetol., 47 Suppl. 1, 35-46.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.39 | additional information | the levels of cardiac chymase expression and activity are markedly increased in the hamster hearts in both the control diabetic and insulin-treated diabetic groups as compared with normal hamsters | Mesocricetus auratus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.39 | chymostatin | - |
Mesocricetus auratus |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.39 | Mesocricetus auratus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.39 | myocardium | - |
Mesocricetus auratus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.39 | angiotensin I + H2O | hamster chymase cleaves the Phe8-His9 bond of angiotensin I | Mesocricetus auratus | angiotensin II + His-Leu | - |
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Release 2023.1 (January 2023)
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